Oregano Oil : One the most effective antibiotics known to science

Oregano oil is the ultimate antibiotic. Oregano is a powerful herb with unique healing properties. Did you know that oregano has eight times more antioxidants than apples and three times as much as blueberries? Antioxidants are needed to protect our body against free radical damage. They boost the immune-system naturally. Oregano Oil is the most potent plant oil in the world!

The distribution of oregano oil started in Ancient Greece. In Greek the word oregano is translated as joy of the mountains. The Greeks were first to use oil for medicinal purposes, such as a powerful antiviral, antibacterial, antiseptic, antifungal agent and also as a remedy for pain, and inflammation. It was the main antibacterial tool used by Hippocrates. Oregano leaves were traditionally used to treat illnesses related to the respiratory and digestive systems.

The Complete Book of Essential Oils and Aromatherapy: Over 600 Natural, Non-Toxic and Fragrant Recipes to Create Health — Beauty — a Safe Home Environment

Oregano Oil is The Ultimate Antibiotic
Main Ingredients Oregano Essential Oil is a mineral density powerhouse. It contains calcium, magnesium, zinc, iron, potassium, copper, boron, manganese, vitamins C, A (beta-carotene), Niacin.

Oregano oil contains four main groups of chemicals which are active healing agents.

Phenols including carvacrol and thymol. They act as antiseptics and antioxidants. Terpenes including pinene and terpinene. They possess antiseptic, antiviral, anti-inflammatory and anesthetic properties. Linalool and bonreol are two long-chain alcohols found in oregano oil. They exhibit antiviral and antiseptic properties. Esters include linalyl acetate and geranyl acetate. They exhibit antifungal properties. Although all these compounds possess healing properties, the most significant primary compound found in oregano oil is carvacrol. Scientific research has proved carvacrol to be one of the most effective antibiotics known to science.

Not All Oregano Oil is Created Equal

Real wild Mediteranean Oregano needs to be either of origanum vulgare kind, or Thymus capitatus, which mostly grows in Spain. It is very important to make sure the Oil of Oregano is derived from these two kinds. It also has to have the carvacrol concentration of 70% or more. Most importantly, oregano essential oil does not create harmful strains in the body and does not have side effects the pharmaceutical antibiotics do. Moreover, it is effective against a dangerous and even deadly bacteria, but does not produce biological changes in the body. Oregano essential oil nourishes the body and doesn’t deplete it of nutrients like conventional antibiotics do. And if you look at the statistics, people in the Mediterranean live longer for the most part. Maybe partly because of oregano which is added to most Mediterranean dishes!

Source: livingtraditionally.com

Don’t Laugh. Rectal Suppositories Could Be the Future of Medicinal Cannabis.

Any people can’t help but laugh the first time they hear the phrase “cannabis suppository.” But don’t be mistaken: This method of accessing the active ingredients in the cannabis is no joke. And the benefits are convincing a growing number Europe’s medical patients to make the switch from more traditional methods of consumption.

Until about five years ago, the vast majority of Europeans who treated their ailments with cannabis either smoked or vaporized the plant. But thanks largely to Rick Simpson, a Canadian who treated his cancer with cannabis oil and lived in exile in Eastern Europe between 2009 and 2013, more and more people started to discover the amazing properties of extracts. There was one big problem: Consuming extracts that had a high THC percentage—up to 90 percent in some cases—was overwhelming for many patients, especially those without previous experience with cannabis.
The benefits of suppositories—combined with how easy it is to make them at home—has made them quite popular.
“Some six years ago, after meeting with Rick Simpson, I started to produce extracts and provide them to many sick people. Illegally, of course,” said a producer in the Czech Republic who asked to go by Martin T. “But lots of them could not bear the psychoactive effects of THC.”
This prompted some patients and their caregivers to look for another way of ingesting the medicine. “I tried to infuse cocoa butter—with a little bit of shea butter and coconut oil—with the extract and made rectal suppositories,” Martin said. “Patients immediately loved them, especially those with digestive and urinary issues.”
Rectal suppositories seemed promising for at least two reasons. First, they go to work quickly. Suppositories exert systemic effects when they enter the rectal mucosa, spreading healing compounds quickly through nearby organs and into the bloodstream. Second, it’s an effective way of diminishing the “head-high” psychoactive effects of THC.
The benefits of suppositories—combined with how easy it is to make them at home—has made them quite popular, especially in Central Europe.
Despite the emergence of vaginal suppositories in the U.S., the suppositories Martin makes are for rectal use only. “A vagina has a very sensitive and specific environment, requiring a special gel carrier, which is pretty hard to get,” he explained. About 90 percent of his patients are now using only suppositories, he said, and the results have been amazing.

Source Leafly

Cannabis Appears to Affect Emotional Response to Pain

New study finds that the use of cannabis does not affect major brain changes in regards to pain, but does appear to provide emotional relief.

Chronic pain affects millions of people around the world. The cause of pain can be very hard or even impossible to detect, and it can be difficult to find an effective form of therapy. Even when the cause is clear, it can be a challenge to find a way to effectively combat ongoing pain.

For some patients who struggle with chronic pain, cannabis (also known as marijuana) and cannabis-based medications have been found to be effective. However, others find that it fails to reduce their pain, only bringing about the side effects associated with its use, which, according to the National Institute on Drug Abuse, include “distorted perceptions, impaired coordination, difficulty with thinking and problem solving, and disrupted learning and memory.”

A new study by the University of Oxford, published in the journal Pain, aims to get a better look at what exactly occurs in the brain when someone uses cannabis as a therapy for pain relief. Researchers found that, although some people reported changes in their levels of pain, there appeared to be no significant changes in the parts of the brain that account for the experience of pain. It did, however, appear that cannabis affects the emotional response the patients to pain, but it does not do so in a consistent fashion.

The Expert Take
Dr. Michael Lee of the University of Oxford’s Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB), who was involved with the study, spoke with Healthline about how the study was conducted, as well as its implications for patients suffering from chronic pain.

Although the study was limited to a small group of men and examined only one possible THC compound, the study was intended to begin scratching the surface of what occurs in the brain during the use of THC (the psychoactive ingredient in cannabis).

“Patients may be prescribed multiple doses and for much longer periods of time to help them manage pain,” explains Lee. “We studied effects from a single dose of THC in healthy, drug-naïve volunteers for ethical and scientific reasons.”

Source and Method
The study involved 12 men in good health, who were each given a 15mg tablet of either THC or a placebo. THC, or tetrahydrocannabinol, is the ingredient in cannabis that produces a high, and accounts for the popularity of cannabis’ use as a recreational drug.

“THC is the main psychoactive compound of cannabis,” explains Lee. “It has been prescribed in the form of Marinol (US) or Dronabinol (Europe) and also as part of Sativex for chronic pain.”

In order to produce a mild amount of pain in these healthy individuals, one of two types of cream was rubbed into the skin of one leg. One type was a dummy cream that did not elicit pain, while the other contained one percent capsaicin, which causes a painful, burning sensation.

Magnetic resonance imaging (MRI) was conducted four times on each participant—once for each possible combination of cream, placebo, and THC. They were asked to explain to researchers the intensity of their pain, as well as how much it bothered them.

The Takeaway
It was not clear that cannabis had any actual effects on the parts of the brain that signal pain, but it did appear to aid some study participants in their emotional experience of that pain.

“Cannabis may influence the emotional aspect (‘the hurt’), rather than the sensation of pain,” explains Lee. “This sort of pain relief may depend on how the amygdala (the brain region linked to fear) reacts to the drug. That means that not everyone can benefit from the effects of cannabis on the brain.”

The researchers found an apparent correlation between the effectiveness of THC for pain relief and a certain connection in the brain—namely, the strength of the connection between the right amygdala and the primary sensorimotor area, which is part of the brain’s cortex. If this correlation is, in fact, present, it may allow doctors to determine in advance whether THC will be effective as a form of pain relief for certain patients. This will, however, require long-term studies, and would also require the participation of patients suffering from chronic pain.

Researchers determined that, although the burning sensation did not appear to change, THC did appear to make the pain less bothersome in some patients. However, out of the 12 participants, only six said there was an actual change in the degree to which their pain bothered them.

Other Research
A 2002 study in Pain Research & Management took a look at therapeutic cannabis use among patients experiencing chronic pain. Most of the patients surveyed in the study reported improvement in pain, mood, and sleep.

Future studies will need to examine the effects of THC over a longer period of time, and in patients who actually experience chronic pain, as opposed to the healthy men surveyed in the Oxford study.

“We do need longer-term studies to help predict which patients, or what sort of pain, might respond positively to cannabis-based medicines,” says Lee. “We also need to understand the long-term risks of cannabis in these patients.”

Although the findings of the Oxford study will likely impact future research on THC and pain relief, it is unclear how the findings will affect the dialogue surrounding the use of cannabis. “The findings are of interest scientifically, but it remains to be seen how they impact the debate about use of cannabis-based medicines,” says Lee in a press release for the study.

Source: Health Line

Study: Cannabidiol (CBD) May Prevent Degenerative Disc Disease

What is Intervertebral Disc Degeneration/Degenerative Disc Disease?
Intervertebral discs sit between each vertebra (bone segments of the spine) and are comprised of fibrous cartilage. They act to stabilize and mobilize the spine, and also to absorb shock that results from movement, in order to prevent damage to the body. When intervertebral discs are damaged and degenerate (most commonly in the regions of the neck and lower back), the spine loses stability and mobility, and several complications can arise, including osteoarthritis (vertebrae start to rub together), herniation (discs bulge out and may compress nerves), and spinal stenosis (the spinal canal, where the spinal cord travels, gets smaller and may also compress nerves). Symptoms experienced with these complications may include pain, numbness, tingling, and disordered movement and can be severely debilitating.
vertibraeIntervertebral disc degeneration may occur as a result of several processes, including inflammation and decreases in available oxygen, water and sugar chains (a main component of intervertebral discs). Intervertebral disc degeneration occurs more commonly as people age, and is more likely to develop in those who are obese, smoke cigarettes, who frequently perform heavy manual labor, or who experience trauma from a fall.
Given that the spine is the body’s main frame of support, maintaining spinal health is vital to leading a long and active life.
Researchers Study CBD-Based Treatments
The results of a controlled animal study published in PLoS One in December 2014 suggest that administration of cannabidiol (CBD), a non-psychoactive cannabinoid (known for its numerous potential health benefits including inflammation and pain reduction), may be useful in reducing damage caused by intervertebral disc degeneration.
Researchers studied 19 rats and created a model of human intervertebral disc degeneration by using needle punctures to injure intervertebral discs of the tailbone area of the rats’ spines. The subjects were then split into three groups, and each immediately treated with a different concentration of CBD (30, 60, or 120 nmol). The discs were then examined using MRI (magnetic resonance imaging) and histologically (under a microscope, in order to see the injuries in finer detail).
Conclusion
MRI analysis showed that treatment with 30 and 60 nmol of CBD did not result in improvements in injury. However, the group that had been administered 120 nmol of CBD did experience reduced damage. By MRI, improvements were noted within 2 days of injury/treatment, and they endured until at least day 15 post-injury/treatment (the last day of the experiment) when examined by MRI and histologically.
Although the sample size of this study was very small, the researchers note, “Considering that cannabidiol presents an extremely safe profile and is currently being used clinically, these results suggest that this compound could be useful in the treatment of intervertebral disc degeneration… Although further research is necessary to clarify the mechanisms involved in CBD effects, the present results suggest the possibility of its use for disc degeneration treatment.”

Source: Medical Jane

HEMP PASTA AND PESTO WITH ROASTED TOMATOES

Ingredients:
Pasta
2 cups hemp flour
2 cups all-purpose flour
1 tsp salt
4 eggs
1 Tbsp hemp oil
Pesto
1/4 cup fresh organic lemon juice
1 cup organic almonds, toasted
2 cloves garlic
1 cup roughly chopped fresh basil
1 cup hemp oil
1 cup hemp seeds
salt and pepper
Roasted Tomatoes
1/2 cup olive oil
4 cups cherry tomatoes, halved
2 bulbs garlic
salt and pepper
Method:
Pasta
1. In a bowl, sift flours and salt. Put mixture on a wooden board or countertop.
2. Make a well in the centre and drop in eggs and oil.
3. Using your fingers, gradually mix flour into liquid until stiff dough forms.
4. Knead for 15 mins.
5. Cover and rest for at least one hr.
6. Using a pasta machine, roll dough from thickness 1 to 4.
7. Cut into desired shapes.
8. Using a cooling rack, allow dough to dry for 30 mins before boiling.
Pesto
1. In a food processor, purée lemon juice, almonds, garlic and basil.
2. While machine is running, drizzle in oil.
3. Transfer contents to a bowl and fold in seeds.
4. With salt and pepper, season to taste.
Roasted Tomatoes
1. Preheat oven to 350˚F.
2. Cut tops off garlic bulbs and drizzle with olive oil.
3. Wrap bulbs in tin foil and roast for 35-40 mins.
4. Lower oven to 275˚F.
5. Squeeze garlic from skins and chop.
6. In a roasting pan, toss tomatoes, oil, salt and pepper. Cook for 30 mins.
7. Transfer tomatoes to a bowl and mix in roasted garlic.
Assembly
1. Boil pasta for 4 mins until al dente.
2. In a bowl, mix tomatoes and a couple spoonfuls of pesto.
3. On a plate, top pasta with tomatoes and pesto.
4. Drizzle with 1-2 Tbsp hemp oil.

Source:Ciao Winnipeg

Cannabis Coconut Oil- Easy Recipe Combats Pain, Nausea, Seizures and More

Virgin coconut oil on it’s own is one of the most amazing products for health care and beauty regimens. I use it to deep condition my hair, moisturize my skin, bake delicious cookies, wipe make up off, apply as a lip-balm, etc.

Coconut oil has tons of health benefits and uses both internally and externally. It can be applied externally to heal skin and hair from damage, or ingested to help improve memory, fight cancer, ease digestion, boost the immune system, reduce inflammation, cure UTIs, eliminated kidney infection, protect the liver and more.

Making a Great Thing Even Better

One way to make coconut oil even more useful is by infusing it with the medicinal properties of marijuana. Marijuana and coconut oil, when combined properly, create a symphony more beautiful than chocolate and peanut butter (it’s just so much sexier than PB&J, people).

Coconut oil is full of natural saturated fats. Don’t worry, these are the ones that increase the HDL (good cholesterol) in your body and help convert the LDL (bad cholesterol) into HDL, a key ingredient to a healthy heart.

The tetrahydrocannabinol (THC) and cannabidiol (CBD) in marijuana, the two cannabinoids that give marijuana it’s healing properties, are very fat soluble. The high concentration of fatty acids present in coconut oil creates a perfect adhesive for the cannabinoids, that bond with the fatty molecules.

How Cannabis Coconut Oil Can Help You

The results of the cannabis coconut oil are much more potent than other butters/margarines/oils, highlighting the medicinal properties of the flower. Cannabis can be used to cure all types of illnesses, depending on the strain, but you have to know how to choose the right one.

Strains heavy in THC are best for treating pain, PTSD, nausea, lack of appetite/eating disorders, asthma, glaucoma and sleep disorders.

Other strains that are higher in CBD can be used to combat anxiety, pain, tumors, cancer, seizures, psychosis and neurodegenerative disorders.

The Marijuana Strain Makes a Difference

Flowers in the sativa family have a high CBD:THC ratio, so they have an energizing affect that stimulates the mind and promotes optimism.

Due to the high CBD content, they are often used to treat depression, ADHD, and appetite loss. Conversely, those in the indica family have a high THC:CBD ratio. The high THC content gives indica strains a sedative effect that helps with anxiety and sleep disorders.

There are many different hybrid plants that fall on a spectrum of traits from both plant families.

Decarb the Marijuana Before Making your Oil

Decarboxylation is a super simple process. Whenever you use marijuana for cooking or recipes like the one below, make sure you follow these easy steps:

Preheat the oven to 240° F. / 115° C.
Break up cannabis flowers and buds into smaller pieces with your hands. We use one ounce, but you can elect to do more or less.
Put the pieces in one layer on a rimmed baking sheet. Make sure the pan is the correct size so there is not empty space on the pan.
Bake the cannabis for 30 to 40 minutes, stirring every 10 minutes so that it toasts evenly.
When the cannabis is darker in color, a light to medium brown, and has dried out, remove the baking sheet and allow the cannabis to cool. It should be quite crumbly when handled.
In a food processor, pulse the cannabis until it is coarsely ground (you don’t want a superfine powder). Store it in an airtight container and use as needed to make extractions
How to Make Cannabis Coconut Oil

In order to prepare Cannabis Coconut Oil, place one gram of de-carboxylate marijuana for every ounce of virgin coconut oil. Place the crushed marijuana in a glass jar and add the coconut oil. Put the lid on the jar, seal it well and put it in a pan full of water. Slowly heat the water and keep it on a below boiling level for 60 minutes.

In this way you will keep the oil safe from overheating.

Next, use a strainer to strain the mixture to eliminate the solid elements. Make sure to squeeze the juice from the cannabis. Some people use cheesecloth to strain the mixture properly.

Once you are done with this procedure, you can eat the cannabis coconut oil like that or use it in other foods or apply it as a lotion. Feel free to cook with this treated oil, only when the temperature is lower than 315 F. That is the temperature of the point of boiling of the active compound of marijuana. Obviously, if you use higher temperatures the effects will be gone.

Source : Wise Mind Healthy Body

New Research Suggests that Endocannabinoid System Helps with Fertility

New evidence gathered from researchers at Bochum and Bonn, headed by Dr Hanns Hatt, has shed light on a little-known area of the endocannabinoid system that has until now been shrouded in mystery.

Dr Hatt’s team has, for the first time, produced a proof of the existence of the GPR18 receptor in sperm cells. GPR18 has for some time been presumed to be a part of the endocannabinoid system, entirely separate from the more well-known CB1 and CB2 receptors. This research provides compelling new evidence that not only is this the case, but that the receptors and their endogenous cannabinoid agonists play a key role in one of the most important biological processes necessary for procreation.

That process is known as the acrosome reaction. The researchers found that GPR18 receptors in sperm cells react to both THC and the endogenous fatty acid N-Arachidonylglycine (NAGly) – a carboxylic analog of the endocannabinoid anandamide – and when activated, trigger the acrosome reaction. During this process, the surface of the sperm is altered as it reaches the egg. Digestive enzymes are released and the sperm loses the ‘cap’ on the anterior half of its head. Without the activation of this previously unknown part of the endocannabinoid system, the sperm would not be capable of penetrating the egg, and fertilisation would be impossible.

Should the research and its findings prove to be correct, this can be considered a pretty huge breakthrough in the science of fertility. The acrosome reaction is among the best ways we have of analysing the ability of semen to fertilise an egg, and given that infertility in men is on the rise, this new understanding of the processes involved in that reaction could hardly have come at a better time.

There’s no guarantee of course that new treatments will necessarily follow this discovery, but it seems likely. Whether those treatments come from the use of endogenous, synthetic, or phyto-cannabinoids remains to be seen, but it certainly casts doubt on previous studies linking cannabis use to infertility. It seems incredibly unlikely that consuming something, which appears to play a direct role in one of the most vitally important processes linked to fertility that we know about, would cause infertility. It just doesn’t add up.

I’m speculating now, but it could well be that this ends up being much like the supposed link between cannabis and schizophrenia. For years (and to this day in many cases) the media and certain scientists reported the link between the two as if it were definitely causal, but subsequent research has led many to now believe that the relationship is far more complex than that. Many individuals suffering from schizophrenia seem to be drawn to cannabis because of the anti-psychotic properties of cannabidiol, rather than the other way around.

The ultimate illustration of this is of course the Keele University meta-analysis of cannabis use and rates of schizophrenia. Cannabis use keeps going up, whilst schizophrenia rates remain level. Clearly the relationship between the two is not as simple as one causing the other, and with this new research illuminating a key function of cannabinoids in fertility, it seems to me that it won’t be long before we start looking at this relationship a little differently too.

Source : The Domestic Extremist
By Deej Sullivan

Cannabis Supercharges Metabolism And Cuts Fat Cells In Half

As cannabis becomes more integrated within mainstream culture, millions are becoming more educated on the many benefits of THC and cannabinoids. Not only does cannabis consumption lower insulin resistance, but it also improves fasting insulin and facilitates metabolic function. More athletes and even those engaged in moderate recreational fitness have incredible benefits from daily consumption of the once demonized plant.

Coupled with the pain-relieving effects of both plant and human-derived cannabinoids, cannabis and exercise seem to go hand in hand if you’re looking to improve your physical health.

Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Insulin helps keeps your blood sugar level from getting too high or too low. If you consume a meal which make blood glucose levels rise quickly, insulin secretion often overshoots to compensate and the excess is stored as fat. If you have too much unused glucose in your cells, you will gain weight. If your body isn’t handling insulin properly, you may also gain weight.

A study published in the American Journal of Medicine has found that regular cannabis consumers have fasting insulin (insulin in your body before eating) levels 16% lower than non-consumers. The study also found that cannabis consumers had 17% lower insulin resistance levels and lower average waist circumferences. The researchers concluded that there were significant associations between marijuana use and smaller waist circumferences.
Some athletes swear by using marijuana or its isolated active ingredients, such as delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) as performance-enhancing drugs, saying these substances ease anxiety and increase pain threshold so that they can push themselves during workouts.

Men’s Journal interviewed elite triathlete Clifford Drusinsky, a Colorado gym owner who also leads training sessions fueled by marijuana edibles.

“Marijuana relaxes me and allows me to go into a controlled, meditational place,” Drusinsky told Men’s Journal. “When I get high, I train smarter and focus on form.”
Researchers say that marijuana has an anti-inflammatory effect and that the chemical compounds that come from weed might mimic the body’s natural endorphins, which could help increase our pain threshold like a natural runner’s high and make it easier to push through a tough workout.

THCs Release During Exercise

Contrary to popular thought, it’s not just the endorphins (the compounds which make you feel excited after activities such as exercise and sex) that make physical activity so great. A 2003 studyfound that exercise actually activates the endocannabinoid system in the same way that the cannabis plant does. The endocannabinoid system is a group of lipids (types of fats) and cell receptors that cannabinoids (compounds like THC and CBD) bind to inside the body. The endocannabinoid system is responsible for easing pain, controlling appetite, and influences mood and memory.

Perhaps as a coping mechanism for easing pain, the body naturally produces its own cannabinoids during exercise. In the aforementioned study, researchers found that human-produced cannabinoids increase as you exercise, causing you to feel a little “high.”

It’s not news to the medical community that the human body stores tetrahydrocannabidiol (THC), the main psychoactive in cannabis, in fat. However, a study put out this August in Drug and Alcohol Dependence has shown that this storage process can give exercisers an extra boost, even up to 28 days after consumption.

As the body begins to burn off fat, small amounts of THC are released back into the bloodstream, producing an effect similar to consuming a small amount of cannabis. THC blood levels increased by approximately 15% immediately after moderate exercise, yet this increase was no longer present two hours after the workout.

Researchers discovered that engaging in exercise can provide you with a stronger buzz and increase the potency of the marijuana. The fact is that working out for just a half hour will trigger an additional stronger high for marijuana users.

This study also showed a correlation between THC release and BMI. The greater the BMI, the greater the increase in THC reintroduced to the body.

Exercise Also Activates the Brain’s Endocannabinoid System

In a 2003 study, researchers uncovered the truth that marijuana and exercise both activate the same endocannabinoid system in the brain.

As a group of lipids, fats, and cell receptors that THC bind to when smoking weed, the endocannabinoid system plays a prominent role in the neurological system for maintaining homeostasis for overall human health. In short, the endocannabinoid system is responsible for easing our pain, controlling our appetite, relieving our stress, influencing our mood, and even regulating our memory. In order to help our body cope with pain from rigorous physical activity, our brain will naturally produce its own version of cannabinoids to stimulate this system during exercise. Just like taking a hit of marijuana, the natural cannabinoids will begin to circulate through the endocannabinoid system when you exercise to produce a high.

Peak blood concentrations of cannabinoids occur in 3-8 minutes after you inhale, as opposed to 60-90 minutes after you eat a weed- or oil-containing edible, with neural effects beginning after 20 minutes and maximizing within a range of 2-4 hours.

THC binds cannabinoid receptor 1 (CB1), mainly localized in the brain, while cannabinol (CBN) binds CB2, which exists mainly on immune cells. CBD binds neither receptor, but still affects numerous metabolic processes including appetite, pain sensation, immune function, stress reactivity, hormonal secretions, and muscle and fat tissue signaling.

A 2013 adjusted epidemiological study showed that obesity rates are significantly lower for all groups of cannabis users (inclusive of gender and age) compared to those who had not used cannabis in the last 12 months.

The lower Body Mass Index (BMI) of pot-smokers may be explained by an adaptive down-regulation of brain endocannabinoid signaling. While acute THC stimulates appetite, the repeated stimulation of CB1 receptors by THC decreases receptor expression and sensitivity, and long-term stimulation may result in antagonistic rather than agonistic triggering of CB1 receptors, which would dampen hunger signals.

Furthermore, CBD and another component of marijuana, tetrahydrocannabivarin (THCV), may reduce body weight, as animal models of obesity have shown THCV to increase metabolism of fat cells. But before you get excited that marijuana may burn fat, please realize that very few strains on the market have significant levels of THCV, so do your research (such as these four strains of skinny-pot that won’t bring out the munchies).

Source: Walking Time

Cannabis Compounds Reduce Multi-Drug Resistant Infections

Cannabis Science, Inc. (OTCBB: GFON). Dr. Robert Melamede, PhD., Director and Chief Science Officer, reported to the Board on the current state of research into the use of natural plant cannabinoids to reduce the spread of drug-resistant bacteria, including methicillin-resistant Staphyloccus aureus (MRSA), and the prospects for development of topical whole-cannabis treatments.

According to studies published in the Journal of the American Medical Association and by the Center for Disease Control in 2007, MRSA is responsible for more than 18,500 hospital-stay related deaths each year, and increased direct healthcare costs of as much as $9.7 billion.

Dr. Melamede stated, “Research into use of whole cannabis extracts and multi-cannabinoid compounds has provided the scientific rationale for medical marijuana’s efficacy in treating some of the most troubling diseases mankind now faces, including infectious diseases such as the flu and HIV, autoimmune diseases such as ALS (Lou Gehrig’s Disease), multiple sclerosis, arthritis, and diabetes, neurological conditions such as Alzheimer’s, stroke and brain injury, as well as numerous forms of cancer. One common element of these diseases is that patients often suffer extended hospital stays, risking development of various Staphyloccus infections including MRSA. A topical, whole-cannabis treatment for these infections is a functional complement to our cannabis extract-based lozenge.”

Investigators at Italy’s Universita del Piemonte Orientale and Britain’s University of London, School of Pharmacy reported in the Journal of Natural Products that five cannabinoids – THC, CBD, CBG, CBC, and CBN – “showed potent antibacterial activity” and “exceptional” antibacterial activity against two epidemic MRSA occurring in UK hospitals. The authors concluded: “Although the use of cannabinoids as systemic antibacterial agents awaits rigorous clinical trials, … their topical application to reduce skin colonization by MRSA seems promising. … Cannabis sativa … represents an interesting source of antibacterial agents to address the problem of multidrug resistance in MRSA and other pathogenic bacteria.”

About Cannabis Science, Inc.

Cannabis Science, Inc. is at the forefront of medical marijuana research and development. The Company works with world authorities on phytocannabinoid science targeting critical illnesses, and adheres to scientific methodologies to develop, produce, and commercialize phytocannabinoid-based pharmaceutical products. In sum, we are dedicated to the creation of cannabis-based medicines, both with and without psychoactive properties, to treat disease and the symptoms of disease, as well as for general health maintenance.

Forward-Looking Statements

This Press Release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Act of 1934. A statement containing works such as “anticipate,” “seek,” intend,” “believe,” “plan,” “estimate,” “expect,” “project,” “plan,” or similar phrases may be deemed “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Some or all of the events or results anticipated by these forward-looking statements may not occur. Factors that could cause or contribute to such differences include the future U.S. and global economies, the impact of competition, and the Company’s reliance on existing regulations regarding the use and development of cannabis-based drugs. Cannabis Science, Inc. does not undertake any duty nor does it intend to update the results of these forward-looking statements.

Source:  Cannabis Science, Inc.